Manman Deng Selected Research

disulfiram-copper

7/2021	Disulfiram/copper shows potent cytotoxic effects on myelodysplastic syndromes via inducing Bip-mediated apoptosis and suppressing autophagy.
1/2017	Disulfiram/copper selectively eradicates AML leukemia stem cells in vitro and in vivo by simultaneous induction of ROS-JNK and inhibition of NF-κB and Nrf2.
12/2016	Effective elimination of adult B-lineage acute lymphoblastic leukemia by disulfiram/copper complex in vitro and in vivo in patient-derived xenograft models.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Manman Deng Research Topics

Disease

15	Neoplasms (Cancer) 04/2022 - 12/2016
11	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 05/2022 - 09/2014
10	Leukemia 05/2022 - 01/2017
6	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 09/2021 - 12/2016
3	Alcoholism (Alcohol Abuse) 07/2021 - 12/2016
2	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 12/2021 - 10/2017
2	B-Cell Lymphoma (Lymphoma, B Cell) 01/2021 - 11/2020
2	Lymphoma (Lymphomas) 01/2021 - 01/2018
1	Cardiovascular Diseases (Cardiovascular Disease) 12/2021
1	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL) 09/2021
1	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 07/2021
1	Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular) 01/2021
1	Waldenstrom Macroglobulinemia (Macroglobulinemia) 01/2021
1	Burkitt Lymphoma (Burkitt's Lymphoma) 01/2019
1	Non-Hodgkin Lymphoma (Lymphosarcoma) 01/2019
1	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 01/2019
1	Mantle-Cell Lymphoma (Lymphoma, Mantle Cell) 01/2019
1	Philadelphia Chromosome 10/2017
1	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma (Leukemia, Pre B Cell) 10/2017
1	Hematologic Neoplasms (Hematological Malignancy) 01/2017
1	Arthritis (Polyarthritis) 12/2016

Drug/Important Bio-Agent (IBA)

7	N- (2- amino- 5- fluorobenzyl)- 4- (N- (pyridine- 3- acrylyl)aminomethyl)benzamideIBA 05/2022 - 01/2015
5	apatinibIBA 05/2022 - 01/2018
4	Pharmaceutical PreparationsIBA 05/2022 - 12/2016
4	triptolideIBA 04/2022 - 12/2016
4	Disulfiram (Antabuse)FDA Link 07/2021 - 09/2014
3	Histone Deacetylase InhibitorsIBA 09/2021 - 01/2015
3	disulfiram-copperIBA 07/2021 - 12/2016
3	CopperIBA 07/2021 - 12/2016
3	chiauranibIBA 01/2021 - 01/2018
2	venetoclaxIBA 01/2021 - 01/2020
2	Apoptosis Regulatory ProteinsIBA 01/2020 - 10/2017
1	nutlin 3IBA 04/2022
1	Simvastatin (Zocor)FDA LinkGeneric 12/2021
1	Phosphotransferases (Kinase)IBA 12/2021
1	Imatinib Mesylate (Gleevec)FDA Link 12/2021
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 12/2021
1	Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA 09/2021
1	Idarubicin (4 Demethoxydaunorubicin)FDA LinkGeneric 01/2021
1	Biomarkers (Surrogate Marker)IBA 01/2021
1	Histone Acetyltransferases (Histone Acetyltransferase)IBA 01/2021
1	selinexorIBA 11/2020
1	DNA (Deoxyribonucleic Acid)IBA 01/2020
1	RNA Polymerase II (RNA Polymerase B)IBA 01/2020
1	napabucasinIBA 07/2019
1	olverembatinibIBA 10/2017
1	src-Family KinasesIBA 10/2017
1	bcr-abl Fusion ProteinsIBA 10/2017
1	gossypol acetic acidIBA 10/2017
1	Decitabine FDA Link 08/2017
1	Reactive Oxygen Species (Oxygen Radicals)IBA 12/2016
1	Biological ProductsIBA 12/2016

Therapy/Procedure

2	Drug Therapy (Chemotherapy) 07/2019 - 06/2019
1	Therapeutics 07/2021
1	Stem Cell Transplantation 07/2019
1	Immunotherapy 01/2019